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AttributesValues
rdf:type
rdfs:label
  • Oxaprozin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Oxaprozin
NSC_Code
  • 310839
UMLS_CUI
  • C0603695
CAS_Registry
  • 21256-18-8
FDA_UNII_Code
  • MHJ80W9LRB
Contributing_Source
  • FDA
Chemical_Formula
  • C18H15NO3
Legacy_Concept_Name
  • Oxaprozin
FULL_SYN
  • OxaprozinPTDCP20321
  • 4,5-Diphenyl-2-oxazolepropionic AcidSNNCI
  • OXAPROZINPTFDAMHJ80W9LRB
  • DayproBRNCI
  • Wy 21743CNNCI
  • OxaprozinPTNCI
DEFINITION
  • A nonsteroidal anti-inflammatory drug (NSAID) derivative of oxazole-propionic acid with analgesic and antipyretic properties. As a first generation NSAID inhibitor, oxaprozin binds to and inactivates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory prostaglandins. When inhibiting COX-2, this agent may be effective in relieving pain and inflammation; when inhibiting COX-1, it may produce unacceptable gastrointestinal side effects. (NCI04)NCI
code
  • C29307
is Has_Free_Acid_Or_Base_Form of
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