About: Micellar Paclitaxel     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Micellar Paclitaxel
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Micellar Paclitaxel
UMLS_CUI
  • C1513261
Legacy_Concept_Name
  • Micellar_Paclitaxel
FULL_SYN
  • PaxceedBRNCI
  • Micellar PaclitaxelPTNCI
DEFINITION
  • A systemic administered polymeric micelle containing paclitaxel that may be used for chronic inflammatory diseases, such as rheumatoid arthritis and psoriasis. Paclitaxel, a toxoid, binds to and stabilizes tubulin and inhibits the disassembly of microtubules, thereby inhibiting cell division. Paclitaxel also inhibits metalloproteinase, thereby blocking the activities of matrix metalloproteinases (MMPs) and preventing collagen degradation in cartilage and bone.NCI
code
  • C29256
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