About: Metoprolol Tartrate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Metoprolol Tartrate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Metoprolol Tartrate
UMLS_CUI
  • C0700776
CAS_Registry
  • 56392-17-7
FDA_UNII_Code
  • W5S57Y3A5L
Contributing_Source
  • FDA
Chemical_Formula
  • 2C15H25NO3.C4H6O6
Legacy_Concept_Name
  • Metoprolol_Tartrate
FULL_SYN
  • Metoprolol TartratePTNCI
  • METOPROLOL TARTRATEPTFDAW5S57Y3A5L
  • LopressorBRNCI
DEFINITION
  • The tartrate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol tartrate antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction, and consequently a diminished cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thus decreasing sympathetic activation, including vasoconstriction, aldosterone secretion.NCI
code
  • C29255
is Has_Salt_Form of
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