About: Magnesium Citrate

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Attributes	Values
rdf:type	Class
rdfs:label	Magnesium Citrate
rdfs:subClassOf	Dietary Supplement
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Magnesium Citrate
UMLS_CUI	C0126774
CAS_Registry	3344-18-1
FDA_UNII_Code	RHO26O1T9V
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	480467
PDQ_Closed_Trial_Search_ID	480467
Chemical_Formula	2C6H5O7.3Mg
Legacy_Concept_Name	Magnesium_Citrate
FULL_SYN	Magnesium CitratePTNCI MAGNESIUM CITRATEPTFDARHO26O1T9V CitromaBRNCI Citrate of MagnesiaSYNCI CitroMagBRNCI CitramagBRNCI
DEFINITION	The citrate salt of the element magnesium with cathartic activity. The cathartic action of magnesium cations appears to result, in part, from osmotically mediated water retention, which subsequently stimulates peristalsis. In addition, magnesium ions may also stimulate the activity of nitric oxide (NO) synthase and increase the biosynthesis of the phospholipid proinflammatory mediator platelet activating factor (PAF) in the gut. NO may stimulate intestinal secretion via prostaglandin- and cyclic GMP-dependent mechanisms while PAF produces significant stimulation of colonic secretion and gastrointestinal motility.NCI
code	C29241

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