About: Burkitt Lymphoma

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Attributes	Values
rdf:type	Class
rdfs:label	Burkitt Lymphoma
equivalentClass	nodeID://b630504
Semantic_Type	Neoplastic Process
Preferred_Name	Burkitt Lymphoma
UMLS_CUI	C0006413
ALT_DEFINITION	An aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma that occurs most often in children and young adults. The disease may affect the jaw, central nervous system, bowel, kidneys, ovaries, or other organs. There are three main types of Burkitt lymphoma (sporadic, endemic, and immunodeficiency related). Sporadic Burkitt lymphoma occurs throughout the world, and endemic Burkitt lymphoma occurs in Africa. Immunodeficiency-related Burkitt lymphoma is most often seen in AIDS patients.NCI-GLOSS
ICD-O-3_Code	9687/3
Neoplastic_Status	Malignant
Legacy_Concept_Name	Burkitt_s_Lymphoma
FULL_SYN	Burkitt's lymphomaPTNCI-GLOSSCDR0000045203 Small Non-Cleaved Cell Lymphoma, Burkitt's TypeSYNCI Burkitt LymphomaPTNCI Burkitt's LymphomaSYNCI Burkitt LymphomaSYNCITCGA
DEFINITION	A highly aggressive lymphoma composed of monomorphic medium-sized B-cells with basophilic cytoplasm and numerous mitotic figures. It is often associated with the presence of Epstein-Barr virus (EBV) and is commonly seen in AIDS patients. Three morphologic variants are recognized: classical Burkitt lymphoma, Burkitt lymphoma with plasmacytoid differentiation, and atypical Burkitt/Burkitt-like lymphoma. All cases express the MYC translocation [t(8;14)]. (WHO, 2001)NCI
code	C2912
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