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AttributesValues
rdf:type
rdfs:label
  • Imipramine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Imipramine Hydrochloride
NSC_Code
  • 114900
UMLS_CUI
  • C0589978
CAS_Registry
  • 113-52-0
FDA_UNII_Code
  • BKE5Q1J60U
Contributing_Source
  • FDA
Chemical_Formula
  • C19H24N2.HCl
Legacy_Concept_Name
  • Imipramine
CHEBI_ID
  • CHEBI:5882
FULL_SYN
  • Imipramine HydrochloridePTDCP30058
  • Imipramine HydrochloridePTNCI
  • IMIPRAMINE HYDROCHLORIDEPTFDABKE5Q1J60U
  • TofranilBRNCI
DEFINITION
  • The hydrochloride salt form of imipramine, a synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects. Imipramine has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. (NCI04)NCI
code
  • C29116
is Has_Salt_Form of
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