About: Doxazosin Mesylate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Doxazosin Mesylate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Doxazosin Mesylate
UMLS_CUI
  • C0678136
CAS_Registry
  • 77883-43-3
FDA_UNII_Code
  • 86P6PQK0MU
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat high blood pressure and urinary problems caused by an enlarged prostate. It relaxes muscle tissue in blood vessels and in the prostate. Cardura is a type of alpha blocker.NCI-GLOSS
Chemical_Formula
  • C23H25N5O5.CH4O3S
Legacy_Concept_Name
  • Doxazosin_Mesylate
CHEBI_ID
  • CHEBI:4709
FULL_SYN
  • doxazosin mesylatePTNCI-GLOSSCDR0000562552
  • Doxazosin MesylatePTDCP32047
  • CarduraPTNCI-GLOSSCDR0000562725
  • Doxazosin MesylatePTNCI
  • CarduraBRNCI
  • DOXAZOSIN MESYLATEPTFDA86P6PQK0MU
  • doxazosinPTNCI-GLOSSCDR0000543115
DEFINITION
  • The mesylate salt form of doxazosin, a quinazoline compound with smooth muscle relaxing activity. Doxazosin mesylate selectively antagonizes alpha-1-adrenergic receptors in smooth muscle of the bladder neck and prostate, thereby relaxing the smooth muscle and decreasing the obstruction and urethral resistance seen with benign prostate hyperplasia (BPH). This may improve BPH symptoms. This agent also blocks alpha-1-adrenergic receptors in peripheral vascular smooth muscle, which leads to vasodilatation and a subsequent decrease in peripheral vascular resistance.NCI
code
  • C29005
is Has_Salt_Form of
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