About: Dichloroallyl Lawsone     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Dichloroallyl Lawsone
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Dichloroallyl Lawsone
NSC_Code
  • 126771
UMLS_CUI
  • C0057845
CAS_Registry
  • 36417-16-0
Legacy_Concept_Name
  • Dichloroallyl_Lawsone
FULL_SYN
  • Dichloroallyl LawsonePTNCI
DEFINITION
  • A triazine derivative with antineoplastic activity. Dichloroallyl lawsone inhibits mitochondrial dihydroorotate dehydrogenase (DHOD), an enzyme that catalyzes the only redox step in de novo pyrimidine biosynthesis, and nucleotide (RNA and DNA) biosynthesis. (NCI04)NCI
code
  • C28959
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