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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cefprozil
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
Preferred_Name
  • Cefprozil
UMLS_CUI
  • C0053882
CAS_Registry
  • 121123-17-9
FDA_UNII_Code
  • 4W0459ZA4V
Contributing_Source
  • FDA
Legacy_Concept_Name
  • Cefprozil
FULL_SYN
  • CEFPROZILPTFDA4W0459ZA4V
  • BMY 28100CNNCI
  • CefprozilPTNCI
  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2R)-amino(4-hydroxyphenyl)acetyl)amino)-8-oxo-3-(1-propenyl)-, (6R,7R)-SNNCI
DEFINITION
  • A semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefprozil's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefprozil inhibits bacterial septum and cell wall synthesis formation.NCI
code
  • C28917
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