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AttributesValues
rdf:type
rdfs:label
  • Bumetanide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
Preferred_Name
  • Bumetanide
UMLS_CUI
  • C0701009
CAS_Registry
  • 28395-03-1
FDA_UNII_Code
  • 0Y2S3XUQ5H
Contributing_Source
  • FDA
Chemical_Formula
  • C17H20N2O5S
Legacy_Concept_Name
  • Bumetanide
CHEBI_ID
  • CHEBI:3213
FULL_SYN
  • BumexBRNCI
  • BUMETANIDEPTFDA0Y2S3XUQ5H
  • BumetanidePTNCI
DEFINITION
  • A potent sulfamoylanthranilic acid derivative belonging to the class of loop diuretics. In the brain, bumetanide may prevent seizures in neonates by blocking the bumetanide-sensitive sodium-potassium-chloride cotransporter (NKCC1), thereby inhibiting chloride uptake thus, decreasing the internal chloride concentration in neurons and may block the excitatory effect of GABA in neonates.NCI
code
  • C28875
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