About: Innate Bone Remodeling     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Innate Bone Remodeling
rdfs:subClassOf
Semantic_Type
  • Cell Function
Preferred_Name
  • Innate Bone Remodeling
UMLS_CUI
  • C1512778
Legacy_Concept_Name
  • Innate_Bone_Remodeling
FULL_SYN
  • Innate Bone RemodelingPTNCI
  • Normal Bone RemodelingSYNCI
  • Biological Bone RemodelingSYNCI
DEFINITION
  • Innate Bone Remodeling takes place in the adult skeleton at discrete foci. The continuous turnover of bone matrix and mineral that involves first, an increase in bone resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). This process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.NCI
code
  • C28754
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