About: M-Phase Promoting Factor     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • M-Phase Promoting Factor
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • M-Phase Promoting Factor
UMLS_CUI
  • C0079805
Legacy_Concept_Name
  • M-Phase_Promoting_Factor
FULL_SYN
  • M-Phase Promoting FactorPTNCI
  • Mitosis-Promoting FactorSYNCI
  • MPFSYNCI
DEFINITION
  • M Phase-Promoting Factor is a protein kinase complex that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.NCIfrom http://www.online-medical-dictionary.org/medical-dictionary-m/M-Phase-Promoting-Factor.htm
code
  • C28557
is someValuesFrom of
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