About: Tyrosine-Protein Kinase JAK3     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Tyrosine-Protein Kinase JAK3
equivalentClass
OMIM_Number
  • 600173
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Enzyme
Preferred_Name
  • Tyrosine-Protein Kinase JAK3
UMLS_CUI
  • C0253457
Legacy_Concept_Name
  • Janus_Kinase-3
FULL_SYN
  • Janus Kinase 3SYNCI
  • JAK3SYNCI
  • Tyrosine-Protein Kinase JAK3PTNCI
Swiss_Prot
  • P52333
DEFINITION
  • Tyrosine-protein kinase JAK3 (1124 aa, ~125 kDa) is encoded by the human JAK3 gene. This protein is involved in T-cell development, immunity, signaling and tyrosine phosphorylation.NCI
DesignNote
  • Janus kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and of a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs.
code
  • C28492
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