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AttributesValues
rdf:type
rdfs:label
  • Actinomycin F1
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Antibiotic
Preferred_Name
  • Actinomycin F1
UMLS_CUI
  • C1515876
CAS_Registry
  • 1402-44-4
Legacy_Concept_Name
  • Actinomycin_F1
FULL_SYN
  • Actinomycin F1PTNCI
  • KS4CNNCI
  • Actinomycin KS4SYNCI
DEFINITION
  • A chromopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces chrysomallus. Actinomycin F1 intercalates into the minor groove of DNA and binds to topoisomerase II, leading to the inhibition of DNA replication and RNA and protein synthesis. (NCI04)NCI
code
  • C2844
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