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AttributesValues
rdf:type
rdfs:label
  • Sho-Saiko-To
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Sho-Saiko-To
UMLS_CUI
  • C1138004
In_Clinical_Trial_For
  • Following Removal of Liver Cancer by Embolization in Treating Patients with Liver Cancer that Cannot be Surgically Removed and Chronic Hepatitis C.
ALT_DEFINITION
  • A Japanese formulation of seven Chinese herbs that is being studied as a treatment for cancer.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 38708
PDQ_Closed_Trial_Search_ID
  • 38708
Legacy_Concept_Name
  • Sho-Saiko-To
FULL_SYN
  • Xiao-Chai-Hu-TangPTDCP00977
  • Sho-Saiko-ToPTNCI
  • Minor Bupleurum FormulaSYNCI
  • Sho-saiko-toPTNCI-GLOSSCDR0000302463
  • TJ-9CNNCI
  • Xiao Chai Hu TangSYNCI
  • Xiao-Chai-Hu-TangSYNCI
  • Keisho-ToSYNCI
DEFINITION
  • A botanical formulation with potential chemopreventive activities. Sho-Saiko-to, an herbal mixture, contains seven herbal extracts whose mechanism of action if not fully understood. There is evidence of antiproliferative effects against hepatocellular carcinoma in vitro. Other effects of this agent described in animal models include the prevention of liver injury and hepatocyte-regenerating activity. Antitumor effects associated with this herbal product may include induction of apoptosis, cell cycle arrest at the G0/G1 phase, and activation of an immune response, characterized by the release of cytokines as well as activation of effector cells, such as macrophages and natural killer cells.NCI
code
  • C2690
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