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AttributesValues
rdf:type
rdfs:label
  • Modafinil
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Modafinil
UMLS_CUI
  • C0066677
CAS_Registry
  • 68693-11-8
Accepted_Therapeutic_Use_For
  • Narcolepsy
In_Clinical_Trial_For
  • Fatigue in patients receiving chemotherapy; Cognitive function in patients with Schizophrenia; Attention deficit/hyperactivity disorder; fatigue in MS patients; depression.
FDA_UNII_Code
  • R3UK8X3U3D
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that is being studied as a treatment for fatigue in patients with cancer. It belongs to the family of drugs called stimulants.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 256449
PDQ_Closed_Trial_Search_ID
  • 256449
Chemical_Formula
  • C15H15NO2S
Legacy_Concept_Name
  • Modafinil
FULL_SYN
  • MODAFINILPTFDAR3UK8X3U3D
  • ProvigilBRNCI
  • ModafinilPTNCI
  • modafinilPTNCI-GLOSSCDR0000269423
DEFINITION
  • A synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. (NCI04)NCI
code
  • C26661
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