About: DEAD/H Box Protein 16     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • DEAD/H Box Protein 16
rdfs:subClassOf
OMIM_Number
  • 603405
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Biologically Active Substance
Preferred_Name
  • DEAD/H Box Protein 16
UMLS_CUI
  • C1333211
Legacy_Concept_Name
  • DEAD-H_Box_Protein-16
FULL_SYN
  • PRP8 HomologSYNCI
  • DEAD/H Box 16SYNCI
  • DDX16 ProteinSYNCI
  • DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 16SYNCI
  • Putative Pre-mRNA Splicing Factor RNA HelicaseSYNCI
  • DBP2SYNCI
  • DDX16SYNCI
  • ATP-Dependent RNA Helicase 3SYNCI
  • DEAH-Box Protein 2SYNCI
  • DEAH-Box Protein 16SYNCI
  • DEAD/H Box Protein 16PTNCI
Swiss_Prot
  • O60231
DEFINITION
  • Encoded by human DDX16 Gene (DEAD/H Subfamily, member 16), ubiquitous 1041-amino acid 119.3-kD nuclear DEAD/H Box Protein 16 is a functional homolog of the Prp8/cdc28 cell cycle progression protein (S. pombe), similar to DEAH box proteins that act as splicing factors. DBP2 is a probable ATP-binding RNA helicase involved in pre-mRNA splicing. DEAD box proteins, characterized by a conserved Asp-Glu-Ala-Asp (DEAD) motif, are putative RNA helicases that alter RNA secondary structure and influence translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on distribution, some family members may be involved in embryogenesis, spermatogenesis, and cellular growth and division. (from LocusLink, Swiss-Prot, OMIM, and NCI)NCI
code
  • C26213
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