About: Ubiquitin Ligase Gene

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Attributes	Values
rdf:type	Class
rdfs:label	Ubiquitin Ligase Gene
rdfs:subClassOf	Ligase Gene nodeID://b722013
Semantic_Type	Gene or Genome
Preferred_Name	Ubiquitin Ligase Gene
UMLS_CUI	C1336849
Legacy_Concept_Name	Ubiquitin_Ligase_Gene
FULL_SYN	Ubiquitin Ligase Component GeneSYNCI Ubiquitin Ligase GenePTNCI
DEFINITION	Ubiquitin Ligase Genes encode eukaryotic enzymes (Ubiquitin Ligases) involved in de/ubiquitination of cellular proteins with ubiquitin through its C-terminus. Regulating the half-lives of many proteins by targeting them for degradation, ubiquitination is associated with many regulated events including protein degradation, chromatin remodeling, heat shock, cell cycle progression, differentiation, antigen presentation, retrovirus assembly, apoptosis, signal transduction, transcriptional activation, biological clocks, receptor down regulation, and endocytosis. (NCI)NCI
code	C26066
is rdfs:subClassOf of	MAP3K1 Gene UBE2D2 Gene UBE3A Gene MYCBP2 Gene CDC34 Gene TRIM36 Gene RNF20 Gene MIB1 Gene VHL Gene FBXW7 Gene RNF139 Gene CBLB Gene NEDD4 Gene CHFR Gene PARK2 Gene TRIP12 Gene SIAH2 Gene FANCL Gene UBE2C Gene TRIM21 Gene WWP2 Gene CCNB1IP1 Gene TRIM33 Gene WWP1 Gene RNF146 Gene
is someValuesFrom of	nodeID://b722016

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