About: Epithelial Discoidin Domain-Containing Receptor 1     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Epithelial Discoidin Domain-Containing Receptor 1
equivalentClass
OMIM_Number
  • 600408
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Enzyme
  • Receptor
Preferred_Name
  • Epithelial Discoidin Domain-Containing Receptor 1
UMLS_CUI
  • C0294276
Legacy_Concept_Name
  • Epithelial_Discoidin_Domain_Receptor-1
FULL_SYN
  • EC 2.7.10.1SYNCI
  • DDR1SYNCI
  • TRKESYNCI
  • NTRK4SYNCI
  • CD167 Antigen-Like Family Member ASYNCI
  • Discoidin Receptor Tyrosine KinaseSYNCI
  • Neurotrophic Tyrosine Kinase Receptor Type 4SYNCI
  • CD167A AntigenSYNCI
  • Epithelial-Specific Receptor KinaseSYNCI
  • Discoidin Domain ReceptorSYNCI
  • Protein-Tyrosine Kinase 3ASYNCI
  • Tyrosine Kinase Receptor ESYNCI
  • HGK2SYNCI
  • Tyrosine-Protein Kinase CAKSYNCI
  • Epithelial Discoidin Domain Receptor 1SYNCI
  • MCK-10SYNCI
  • Receptor Tyrosine Kinase NEPSYNCI
  • CD167aSYNCI
  • Mammarian Carcinoma Kinase 10SYNCI
  • Protein-Tyrosine Kinase RTK 6SYNCI
  • Protein-Tyrosine Kinase RTK-6SYNCI
  • Epithelial Discoidin Domain-Containing Receptor 1PTNCI
  • Tyrosine Kinase DDRSYNCI
  • Cell Adhesion KinaseSYNCI
  • Discoidin Domain Receptor Family Member 1SYNCI
  • Neuroepithelial Tyrosine KinaseSYNCI
Swiss_Prot
  • Q08345
DEFINITION
  • Epithelial discoidin domain-containing receptor 1 (913 aa, ~101 kDa) is encoded by the human DDR1 gene. This protein plays a role in tyrosine phosphorylation, extracellular matrix catabolism and signal transduction.NCI
DesignNote
  • Epithelial discoidin domain-containing receptor 1 has extracellular Discoidin I motifs; GLY/PRO-rich domains likely required for ligand or substrate interaction; a F5/8 type C domain; and a novel N-terminal region with homology to a factor VIII domain. The C-terminal catalytic domain has type II receptor tyrosine kinase motifs.
code
  • C25855
is Has_Target of
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