About: Oglufanide Disodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Oglufanide Disodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Oglufanide Disodium
PubMedID_Primary_Reference
  • 12180893
NCI_META_CUI
  • CL032903
CAS_Registry
  • 237068-57-4
FDA_UNII_Code
  • Q60AU1LLNU
Contributing_Source
  • FDA
ALT_DEFINITION
  • An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 43387
PDQ_Closed_Trial_Search_ID
  • 43387
Chemical_Formula
  • C16H17N3O5.2Na
Legacy_Concept_Name
  • Glufanide_Disodium
FULL_SYN
  • L-Tryptophan, L-alpha-glutamyl-, disodium saltSNNCI
  • IM-862PTNCI-GLOSSCDR0000046201
  • IM862CNNCI
  • IM 862PTDCP31663
  • IM 862CNNCI
  • Glufanide DisodiumSYNCI
  • Oglufanide DisodiumPTNCI
  • ThymogenSYNCI
  • OGLUFANIDE DISODIUMPTFDAQ60AU1LLNU
DEFINITION
  • The disodium salt of a synthetic form of a naturally-occurring dipeptide consisting of L-glutamic acid and L-tryptophan with potential antiangiogenic and potential immunomodulating activities. Oglufanide inhibits vascular endothelial growth factor (VEGF), which may inhibit angiogenesis. This agent has also been reported to stimulate the immune response to hepatitic C virus and intracellular bacterial infections.NCI
code
  • C2558
is someValuesFrom of
is Has_Salt_Form of
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