About: Mutant p53 Peptide Pulsed Dendritic Cell Vaccine

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Attributes	Values
rdf:type	Class
rdfs:label	Mutant p53 Peptide Pulsed Dendritic Cell Vaccine
rdfs:subClassOf	Dendritic Cell Tumor Peptide Vaccine
Semantic_Type	Pharmacologic Substance Immunologic Factor
Preferred_Name	Mutant p53 Peptide Pulsed Dendritic Cell Vaccine
UMLS_CUI	C0879296
In_Clinical_Trial_For	Locally Advanced Non-Small Cell Lung Cancer and Tumor Expressing Mutant p53.
PDQ_Open_Trial_Search_ID	43586
PDQ_Closed_Trial_Search_ID	43586
Legacy_Concept_Name	Mutant_p53_Peptide_Pulsed_Dendritic_Cell_Vaccine
FULL_SYN	mutant p53 peptide pulsed DC vaccineSYNCI Mutant p53 Peptide Pulsed Dendritic Cell VaccinePTNCI dendritic cell vaccine, mutant p53 peptide pulsedSYNCI
DEFINITION	A cancer vaccine consisting of autologous dendritic cells which have been pulsed with a mutant p53 peptide. Vaccination with mutant p53 peptide pulsed dendritic cells may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing mutant p53, resulting in tumor cell lysis. Many tumor cells overexpress mutant p53 proteins, resulting in the loss of apoptosis regulation and abnormal cell proliferation. (NCI04)NCI
code	C2540
is someValuesFrom of	nodeID://b694225

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