About: Iodine I 131 Tositumomab

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Iodine I 131 Tositumomab Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Iodine I 131 Tositumomab
rdfs:subClassOf	Radioimmunoconjugate
Has_Target	Antigens, CD20
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance Immunologic Factor
Preferred_Name	Iodine I 131 Tositumomab
NSC_Code	715813
UMLS_CUI	C0768182
CAS_Registry	192391-48-3
Accepted_Therapeutic_Use_For	CD-20-antigen-expressing, relapsed or refractory, low-grade, follicular, or transformed Non-Hodgkins lymphoma
In_Clinical_Trial_For	Mantle cell lymphoma; Non-Hodgkins lymphoma
FDA_UNII_Code	K1KT5M40JC
Contributing_Source	FDA
ALT_DEFINITION	A monoclonal antibody (tositumomab) that has been chemically changed by adding radioactive iodine, and that is used in the treatment of certain types of non-Hodgkin lymphoma. It belongs to the family of drugs called radioconjugated monoclonal antibodies. When iodine I 131 tositumomab and tositumomab are given together, the combination is called the Bexxar regimen.NCI-GLOSS
PDQ_Open_Trial_Search_ID	42806
PDQ_Closed_Trial_Search_ID	42806
Legacy_Concept_Name	I_131_Monoclonal_Antibody_Anti-B1
FULL_SYN	131-I-Anti-B1 Monoclonal AntibodySYNCI I 131 Monoclonal Antibody Anti-B1SYNCI Iodine-131 TositumomabSYNCI I131-MOAB-B1ABNCI Iodine I 131 TositumomabPTNCI Iodine I 131 MOAB Anti-B1SYNCI Iodine-131 Anti-B1 AntibodySYNCI I 131 TositumomabSYNCI TOSITUMOMAB I-131PTFDAK1KT5M40JC Iodine-131 Anti-CD20 Monoclonal AntibodySYNCI Iodine I 131 Monoclonal Antibody Anti-B1SYNCI iodine I 131 tositumomabPTNCI-GLOSSCDR0000367409
DEFINITION	A monoclonal antibody directed against the CD20 protein expressed on the surface of B-lymphocytes and radiolabeled with the radioisotope iodine I 131 with potential antineoplastic activity. Iodine I 131 tositumomab binds to and selectively delivers cyctotoxic radiation to CD20-expressing B-lymphocytes, thereby minimizing systemic radiotoxicity.NCI
code	C2444
is someValuesFrom of	nodeID://b663024 nodeID://b663280 nodeID://b663336 nodeID://b720093

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 117 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software