About: Aminoglycoside Antibiotic

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Attributes	Values
rdf:type	Class
rdfs:label	Aminoglycoside Antibiotic
rdfs:subClassOf	Antibiotic Protein Synthesis Inhibitor
Semantic_Type	Chemical Viewed Functionally
Preferred_Name	Aminoglycoside Antibiotic
UMLS_CUI	C0002556
ALT_DEFINITION	A family of antibiotics that works against many types of bacteria and includes streptomycin, gentamicin, and neomycin. Aminoglycosides are used to treat bacterial infections.NCI-GLOSS
Legacy_Concept_Name	Aminoglycoside_Antibiotic
CHEBI_ID	CHEBI:22507
FULL_SYN	aminoglycoside antibioticPTNCI-GLOSSCDR0000044812 Aminoglycoside AntibioticPTNCI AminoglycosidesSYNCI Aminoglycoside DrugsSYNCI Aminoglycoside AgentsSYNCI
DEFINITION	Any antibiotic containing amino-modified sugars originally isolated from various Streptomyces and Micromonospora species. Aminoglycoside antibiotics bind to the 16S RNA of the bacterial 30S ribosomal subunit, inhibiting translation and protein synthesis. Aminoglycoside use is associated with ototoxicity, neurotxicity and nephrotoxicity.NCI
code	C2363
is rdfs:subClassOf of	SPECTINOMYCIN HYDROCHLORIDE SPECTINOMYCIN STREPTOMYCIN TOBRAMYCIN KANAMYCIN Sisomicin Kanamycin A Kanamycin A Sulfate Kanamycin C Neamine Sisomicin Sulfate Micronomicin Ribostamycin Spectinomycin Hydrochloride Anhydrous Spectinomycin Sulfate Spectinomycin Sulfate Tetrahydrate Neomycin C Amikacin Sulfate DAPTOMYCIN Dihydrostreptomycin Sulfate Paromomycin Sulfate STREPTOMYCIN SULFATE Gentamicins AMIKACIN Dihydrostreptomycin PAROMOMYCIN Bekanamycin Framycetin GENTAMICIN SULFATE KANAMYCIN SULFATE NEOMYCIN SULFATE NETILMICIN NETILMICIN SULFATE NEOMYCIN CAPREOMYCIN CAPREOMYCIN SULFATE Propikacin Framycetin Sulfate Arbekacin Astromicin Astromicin Sulfate Gentamicin C1 Gentamicin C1a Gentamicin C2 Bekanamycin Sulfate Capreomycin IIB Dibekacin Betamicin Sulfate Betamicin Isepamicin Tobramycin Sulfate Bluensomycin Butikacin

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