About: Ovine Submaxillary Mucin     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Ovine Submaxillary Mucin
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Ovine Submaxillary Mucin
UMLS_CUI
  • C0279238
In_Clinical_Trial_For
  • Colon Cancer.
PDQ_Open_Trial_Search_ID
  • 39375
PDQ_Closed_Trial_Search_ID
  • 39375
Legacy_Concept_Name
  • Ovine_Submaxillary_Mucin
FULL_SYN
  • Ovine Submaxillary MucinPTNCI
  • Ovine SialomucinSYNCI
DEFINITION
  • A naturally occurring mucin glycoprotein. Ovine submaxillary mucin (OSM), extracted from an ovine submaxillary gland, provides a rich source of the sialylated Tn antigen (sTn), which is a carbohydrate antigen found on mucins of many epithelial tumors. Vaccination with OSM may result in the production of antibodies as well as elicitation of a cytotoxic T- lymphocyte (CTL) response against tumor cells expressing sTn, thereby results in decreased tumor cell growth.NCI
code
  • C2350
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