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AttributesValues
rdf:type
rdfs:label
  • Aminolevulinic Acid
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Aminolevulinic Acid
UMLS_CUI
  • C0002563
CAS_Registry
  • 106-60-5
In_Clinical_Trial_For
  • Photosensitizer in chronic lymphocytic leukemia, lymphoma and skin cancer
FDA_UNII_Code
  • 88755TAZ87
Contributing_Source
  • FDA
ALT_DEFINITION
  • The active ingredient in a drug used to treat actinic keratosis (a skin condition that may become cancer). The drug is also being studied in the treatment of squamous cell and basal cell skin cancers and other types of cancer. When aminolevulinic acid is taken up by cells, including cancer cells, and then exposed to certain types of light, it becomes active and kills the cells. It is a type of photosensitizing agent.NCI-GLOSS
Chemical_Formula
  • C5H9NO3
Legacy_Concept_Name
  • Aminolevulinic_Acid
CHEBI_ID
  • CHEBI:17549
FULL_SYN
  • d-Amino-Levulinic AcidSNNCI
  • 5-Aminolaevulinic AcidSYNCI
  • Delta Aminolevulinic AcidSYNCI
  • Delta-Aminolevulinic AcidSYNCI
  • aminolevulinic acidPTNCI-GLOSSCDR0000045532
  • 5-Amino-4-oxopentanoic AcidSNNCI
  • 5-ALAABNCI
  • Aminolevulinic AcidPTNCI
  • Amino-Levulinic AcidSYNCI
  • AMINOLEVULINIC ACIDPTFDA88755TAZ87
  • 5-Aminolevulinic AcidSYNCI
DEFINITION
  • A topically administered metabolic precursor of protoporphyrin IX. After topical administration, aminolevulinic acid (ALA) is converted to protoporphyrin IX (PpIX) which is a photosensitizer. When the proper wavelength of light activates protoporphyrin IX, singlet oxygen is produced, resulting in a local cytotoxic effect. (NCI04)NCI
code
  • C234
is Has_Free_Acid_Or_Base_Form of
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