About: Aminoglutethimide     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Aminoglutethimide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Aminoglutethimide
NSC_Code
  • 330915
UMLS_CUI
  • C0002555
CAS_Registry
  • 125-84-8
FDA_UNII_Code
  • 0O54ZQ14I9
Contributing_Source
  • FDA
ALT_DEFINITION
  • An anticancer drug that belongs to the family of drugs called nonsteroidal aromatase inhibitors. Aminoglutethimide is used to decrease the production of sex hormones (estrogen in women or testosterone in men) and suppress the growth of tumors that need sex hormones to grow.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39140
PDQ_Closed_Trial_Search_ID
  • 39140
Chemical_Formula
  • C13H16N2O2
Legacy_Concept_Name
  • Aminoglutethimide
CHEBI_ID
  • CHEBI:2654
FULL_SYN
  • aminoglutethimidePTNCI-GLOSSCDR0000045170
  • AminoblastinFBNCI
  • AminoglutethimidePTDCP00407
  • alpha-(4-Aminophenyl)-alpha-ethylglutarimideSNNCI
  • 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedioneSNNCI
  • 3-Ethyl-3-(p-aminophenyl)-2,6-dioxopiperidineSNNCI
  • 2-(p-Aminophenyl)-2-ethylglutarimideSNNCI
  • Ba-16038SYDTPNSC0330915
  • EliptenSYDTPNSC0330915
  • 2-(p-Aminophenyl)-2-ethylglutarimideSYDTPNSC0330915
  • AminoglutethimidePTNCI
  • AminoglutethimideSYNCI
  • AMINOGLUTETHIMIDEPTFDA0O54ZQ14I9
  • MamomitFBNCI
  • EliptenSYNCI
  • RodazolFBNCI
  • BA-16038CNNCI
  • CytadrenBRNCI
  • OrimetenFBNCI
  • AminoglutethimideSYDTPNSC0330915
  • OrimeteneFBNCI
  • OrimentenSYNCI
DEFINITION
  • A synthetic derivative of the sedative and anticonvulsant glutethimide with anti-steroid properties. Originally used as an anticonvulsant, aminoglutethimide also blocks adrenal steroidogenesis by inhibiting the enzymatic conversion of cholesterol to pregnenolone. In addition, this agent blocks the peripheral aromatization of androgenic precursors to estrogens. Aminoglutethimide does not suppress ovarian estrogen production.NCI
code
  • C233
is someValuesFrom of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 89 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software