About: 5 Alpha-Reductase Inhibitor

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Attributes	Values
rdf:type	Class
rdfs:label	5 Alpha-Reductase Inhibitor
rdfs:subClassOf	Enzyme Inhibitor
Semantic_Type	Chemical Viewed Functionally
Preferred_Name	5 Alpha-Reductase Inhibitor
UMLS_CUI	C1318898
ALT_DEFINITION	A substance that blocks an enzyme needed by the body to make dihydrotestosterone (a male sex hormone made from testosterone). Dihydrotestosterone can cause the prostate to grow. 5-alpha reductase inhibitors are used to shrink an enlarged prostate gland and to improve the flow of urine in a condition called benign prostatic hyperplasia (BPH). A 5-alpha reductase inhibitor is a type of enzyme inhibitor.NCI-GLOSS
Legacy_Concept_Name	_5_Alpha-Reductase_Inhibitor
CHEBI_ID	CHEBI:50781
FULL_SYN	Steroid 5-alpha-reductase InhibitorSYNCI 5 Alpha-Reductase InhibitorPTNCI 5-alpha reductase inhibitorPTNCI-GLOSSCDR0000651169
DEFINITION	Any substance that inhibits steroid 5-alpha-reductase, an enzyme that converts testosterone into dihydrotestosterone (DHT). Since DHT has three times greater affinity for androgen receptors than testosterone, inhibition of 5-alpha-reductase results in a strong reduction in the androgenic effects of testosterone.NCI
code	C2319
is rdfs:subClassOf of	Idronoxil Izonsteride Turosteride FINASTERIDE DUTASTERIDE Epristeride

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