About: Tumor Necrosis Factor (GEN)     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Tumor Necrosis Factor (GEN)
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Tumor Necrosis Factor (GEN)
UMLS_CUI
  • C1519694
Legacy_Concept_Name
  • Tumor_necrosis_factor_GEN
FULL_SYN
  • Tumor Necrosis Factor (GEN)PTNCI
DEFINITION
  • A recombinant form of endogenous Tumor Necrosis Factor alpha manufactured by Genzyme Pharmaceuticals. Tumor necrosis factor-alpha binds to and activates receptors on the cell surface, resulting in modulation of adipocyte metabolism, lysis of tumor cells, and induction of hemorrhagic necrosis of certain transplantable tumors. (NCI04)NCI
code
  • C2245
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