About: Interferon Alfa-N1     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Interferon Alfa-N1
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Interferon Alfa-N1
NSC_Code
  • 339140
UMLS_CUI
  • C0699817
CAS_Registry
  • 308067-63-2
Accepted_Therapeutic_Use_For
  • Chronic Hepatitis C
In_Clinical_Trial_For
  • AIDS-Associated Kaposi Sarcoma
Legacy_Concept_Name
  • Interferon_Alfa-N1
FULL_SYN
  • Interferon AlfaSYNCI
  • Interferon Alfa-N1PTNCI
  • WellferonBRNCI
  • HumoferonFBNCI
DEFINITION
  • A highly purified alpha interferon produced by a human lymphoid cell line. Interferon alpha-n1 consists of multiple alpha interferon subtypes, at least two of which are glycosylated. In contrast, recombinant alpha interferons are individual non-glycosylated proteins produced from individual alpha interferon genes. Alpha interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose proteins have antiviral, antiproliferative, anticancer, and immune-modulating effects. (NCI04)NCI
code
  • C2220
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