About: Complement Activation

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Complement Activation
rdfs:subClassOf	Immune Response Process nodeID://b661302
Semantic_Type	Molecular Function
Preferred_Name	Complement Activation
UMLS_CUI	C0009528
Legacy_Concept_Name	Complement_Activation
FULL_SYN	Complement ActivationPTNCI
DEFINITION	Any physiologic process in which a protease directs the cleavage of complement components C4, C2, or factor B which then form the C3 and C5 convertases for the classical and lectin pathways, respectively. This process is involved in direct lysis of target cells, immune adherence and phagocytosis of pathogens, and recruitment and activation of immunocompetent cells.NCI
code	C21519
is rdfs:subClassOf of	Negative Regulation of Complement Activation Complement-Dependent Cytotoxicity Activation of Membrane Attack Complex
is someValuesFrom of	nodeID://b652204 nodeID://b652230 nodeID://b652250 nodeID://b654165 nodeID://b654168 nodeID://b654450 nodeID://b654669 nodeID://b654670 nodeID://b655188 nodeID://b655419 nodeID://b660823 nodeID://b661310 nodeID://b661334 nodeID://b661337 nodeID://b661339 nodeID://b661354 nodeID://b661364 nodeID://b661368 nodeID://b661376 nodeID://b681281 nodeID://b682222

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