About: Absent in Melanoma 1     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Absent in Melanoma 1
rdfs:subClassOf
OMIM_Number
  • 601797
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Absent in Melanoma 1
UMLS_CUI
  • C1366838
Legacy_Concept_Name
  • Absent_in_Melanoma_1_Protein
FULL_SYN
  • ST4 ProteinSYNCI
  • ST4SYNCI
  • AIM1SYNCI
  • Absent in Melanoma 1PTNCI
Swiss_Prot
  • Q9Y4K1
DEFINITION
  • Based upon sequence analysis the AIM1 protein appears to be a member of the beta-gamma crystallin superfamily. However, it is the first mammalian member of the family with a primarily non-lens role. Other parts of the predicted AIM1 protein sequence have weak similarity with filament or actin-binding proteins. The authors suggested that AIM1 is a good candidate for the putative suppressor of malignant melanoma on chromosome 6 (Trent et al., 1990), possibly exerting its effects through interactions with the cytoskeleton. (from OMIM)NCI
code
  • C21390
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