About: HIV Budding     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • HIV Budding
rdfs:subClassOf
Semantic_Type
  • Molecular Function
Preferred_Name
  • HIV Budding
UMLS_CUI
  • C1512301
Legacy_Concept_Name
  • HIV_Budding
FULL_SYN
  • HIV BuddingPTNCI
  • HIV BuddingSYNCI
DEFINITION
  • HIV Budding is a process in which newly generated viral RNA and protein complexes are assembled at, packaged in, and released from the cell surface membrane taking a piece of the cell membrane to form their own viral membranes. To bud from infected cells, HIV-1 employs several host proteins such as endosomal sorting protein Tsg101, which functions in the Vps pathway. The L domain (PTAP) in the p6 domain of HIV-1 Gag interacts with the N-terminal domain of TSG101; the Vps28-binding domain of TSG101 inhibits budding.NCI
code
  • C21244
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