About: Transforming Acidic Coiled-Coil-Containing Protein 1     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Transforming Acidic Coiled-Coil-Containing Protein 1
rdfs:subClassOf
OMIM_Number
  • 605301
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Transforming Acidic Coiled-Coil-Containing Protein 1
UMLS_CUI
  • C0907959
Legacy_Concept_Name
  • Transforming_Acidic_Coiled-Coil_Containing_Protein-1
FULL_SYN
  • Transforming Acidic Coiled-Coil-Containing Protein 1PTNCI
  • TACC1 ProteinSYNCI
  • Gastric Cancer Antigen Ga55SYNCI
  • TACC1SYNCI
  • Acidic Coiled-Coil Protein 1SYNCI
  • Taxin 1SYNCI
Swiss_Prot
  • O75410
DEFINITION
  • Transforming acidic coiled-coil-containing protein 1 (805 aa, ~88 kDa) is encoded by the human TACC1 gene. This protein may be involved in cell division and histogenesis.NCI
DesignNote
  • Transforming acidic coiled-coil-containing protein 1 is rich in serine, proline, and acidic residues, with a 20-amino acid N-terminus rich in tryptophan, and contains two nuclear localization signals but no DNA- or RNA-binding domains. A 200-residue C-terminus with extensive alpha-helical segments is expected to adopt a coiled-coil structure. This nuclear protein is concentrated at centrosomes and interacts with microtubules and tubulin. (Swiss-Prot, OMIMI)
code
  • C21225
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