About: Polyamine Synthesis Inhibitor     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Polyamine Synthesis Inhibitor
rdfs:subClassOf
Semantic_Type
  • Chemical Viewed Functionally
Preferred_Name
  • Polyamine Synthesis Inhibitor
UMLS_CUI
  • C1514194
Legacy_Concept_Name
  • Polyamine_Inhibitory_Agent
FULL_SYN
  • Polyamine Synthesis InhibitorPTNCI
  • Polyamine InhibitorSYNCI
DEFINITION
  • A compound that inhibits the synthesis of the naturally occurring polyamines, intracellular compounds that bind to DNA and play a critical role in cell division, differentiation and membrane function. These inhibitors affect the activity of enzymes like ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMD) that are involved in the biosynthesis of polyamines. A reduction in intracellular polyamine concentration may lead to a decreased cell growth.NCI
code
  • C2076
is rdfs:subClassOf of
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