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AttributesValues
rdf:type
rdfs:label
  • TFIIF Subunit Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • TFIIF Subunit Gene
UMLS_CUI
  • C1336614
Legacy_Concept_Name
  • TFIIF_Subunit_Gene
FULL_SYN
  • TFIIF Subunit GenePTNCI
DEFINITION
  • Human TFIIF Subunit Genes, GTF2F1 Gene and GTF2F2 Gene, encode similar alpha (517-aa, 58-kDa, phosphorylated) and beta (249-aa, 28-kDa) subunits of heterodimeric nuclear general transcription initiation factor TFIIF, which binds to and recruits RNA polymerase II to the initiation complex in collaboration with TFIIB. The beta subunit shows ATP-dependent DNA-helicase activity and the region that binds RNA polymerase exhibits similarities with prokaryotic sigma factors. (NCI)NCI
code
  • C20651
is rdfs:subClassOf of
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