About: Tridolgosir Hydrochloride     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Tridolgosir Hydrochloride
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Tridolgosir Hydrochloride
UMLS_CUI
  • C1519648
CAS_Registry
  • 214462-68-7
In_Clinical_Trial_For
  • Chemoprevention; Metastatic Renal and Colorectal Cancer.
FDA_UNII_Code
  • 78KR51ES9B
Contributing_Source
  • FDA
Chemical_Formula
  • C8H15NO3.ClH
Legacy_Concept_Name
  • Tridolgosir_Hydrochloride
FULL_SYN
  • Tridolgosir HydrochloridePTNCI
  • Swainsonine HClSYNCI
  • GD0039CNNCI
  • GD-0039CNNCI
  • TRIDOLGOSIR HYDROCHLORIDEPTFDA78KR51ES9B
  • (1S,2R,8R,8aR)-Octahydro-1,2,8-indolizinetriol HydrochlorideSNNCI
DEFINITION
  • An orally-active synthetic hydrochloride salt form of swainsonine, an inhibitor of Golgi alpha-mannosidase II. Tridolgosir inhibits formation of carbohydrate structures affecting cell-cell adhesion, resulting in decreases in tumor growth or metastasis. This agent also stimulates the immune system. (NCI04)NCI
code
  • C2065
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