About: HMGB Family Gene     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • HMGB Family Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • HMGB Family Gene
UMLS_CUI
  • C1333911
Legacy_Concept_Name
  • HMGB_Family_Gene
FULL_SYN
  • HMGB Family GenePTNCI
Gene_Encodes_Product
  • HMGB Family Protein
DEFINITION
  • Human HMGB Family Genes encode abundant DNA-binding and bending HMG-Box Family proteins (with structure, rather than sequence, specificity) that play an architectural role in nucleoprotein assembly. They have two homologous DNA-binding HMG-box domains connected by a short basic linker to an acidic C-terminus that differs in length. Tail length may be the dominant factor mediating property differences among HMGB proteins and determines DNA-binding properties of the HMG boxes. The tail is essential for DNA-binding. (NCI)NCI
code
  • C20574
is rdfs:subClassOf of
is someValuesFrom of
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