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AttributesValues
rdf:type
rdfs:label
  • HMG Family Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • HMG Family Gene
UMLS_CUI
  • C1333918
Legacy_Concept_Name
  • HMG_Family_Gene
FULL_SYN
  • HMG Family GenePTNCI
Gene_Encodes_Product
  • HMGA Family Protein
  • HMGB Family Protein
  • HMGN Family Protein
DEFINITION
  • Human HMG Family Genes encode ubiquitous non-histone HMG chromatin proteins originally named according to PAGE electrophoretic mobility, shared physical properties, and association with chromatin. Canonical HMG proteins are subdivided into 3 superfamilies with characteristic functional sequence motifs: HMGB (formerly HMG-1/-2), HMGN (formerly HMG-14/-17), and HMGA (formerly HMG-I/Y/C). DNA-binding HMG proteins appear to have roles in matrix stabilization, ssDNA protection, replication, and transcription that influence cell growth, proliferation, differentiation, and death. (NCI)NCI
code
  • C20570
is rdfs:subClassOf of
is someValuesFrom of
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