About: Telomere Length Maintenance

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About: Telomere Length Maintenance Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Telomere Length Maintenance
rdfs:subClassOf	Telomere Maintenance
Semantic_Type	Genetic Function
Preferred_Name	Telomere Length Maintenance
UMLS_CUI	C1515260
Legacy_Concept_Name	Telomere_Length_Maintenance
FULL_SYN	Telomere Length MaintenancePTNCI Length MaintenanceSYNCI
DEFINITION	Telomeres in human cancer cells consist of a tandem array of telomeric DNA repeats bound to a specialized telomeric proteins. Telomeres allow cells to distinguish natural chromosome ends from damaged DNA. When telomere function is disrupted, a potentially lethal DNA damage response can ensue, DNA repair activities threaten the integrity of chromosome ends, and extensive genome instability can arise. Both telomerase and recombination can lengthen telomeres. (from PMID 11850780 and NCI)NCI
code	C20336
is rdfs:subClassOf of	Telomere Recombination Elongation by Telomerase
is someValuesFrom of	nodeID://b717413 nodeID://b717419 nodeID://b717760 nodeID://b718550 nodeID://b719008 nodeID://b719013

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