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AttributesValues
rdf:type
rdfs:label
  • Mediator Complex
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Mediator Complex
UMLS_CUI
  • C1363844
Legacy_Concept_Name
  • Mediator_of_Activation
FULL_SYN
  • Mediator of ActivationSYNCI
  • Mediator of RNA Polymerase II TranscriptionSYNCI
  • Mediator ComplexPTNCI
  • Mediator Coactivator ComplexSYNCI
  • MediatorSYNCI
  • Mediator CoactivatorSYNCI
DEFINITION
  • A protein complex that is involved in the initiation of transcription. This complex is composed of over 30 protein subunits, which binds to the RNA polymerase II holoenzyme complex and facilitates the interaction of transcription factors with the polymerase.NCI
DesignNote
  • The human Mediator complex is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11,MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26,MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. (UniProt)
code
  • C19864
is rdfs:subClassOf of
is someValuesFrom of
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