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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Sipuleucel-T
rdfs:subClassOf
Has_Target
Concept_In_Subset
Semantic_Type
  • Cell
  • Immunologic Factor
Preferred_Name
  • Sipuleucel-T
NSC_Code
  • 720270
UMLS_CUI
  • C1706668
CAS_Registry
  • 917381-47-6
In_Clinical_Trial_For
  • Prostate Cancer
FDA_UNII_Code
  • 8Q622VDR18
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat prostate cancer that has spread. It is made from immune system cells collected from a patient with prostate cancer. The cells are treated with a protein that is made by combining a protein found on prostate cancer cells with a growth factor. When the cells are injected back into the patient, they may stimulate T cells to kill prostate cancer cells. Provenge is a type of vaccine and a type of cellular adoptive immunotherapy.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 38038
PDQ_Closed_Trial_Search_ID
  • 38038
Legacy_Concept_Name
  • APC8015_Vaccine
FULL_SYN
  • SIPULEUCEL-TPTFDA8Q622VDR18
  • Sipuleucel-TPTNCI
  • sipuleucel-TPTNCI-GLOSSCDR0000579628
  • APC8015 VaccineSYNCI
  • APC8015PTNCI-GLOSSCDR0000044966
  • PA2024 (PAP/GM-CSF)-Loaded Dendritic Cell VaccineSYNCI
  • APC8015CNNCI
  • ProvengePTNCI-GLOSSCDR0000579625
  • ProvengeBRNCI
DEFINITION
  • A cell-based vaccine composed of autologous antigen-presenting peripheral blood mononuclear cells (enriched for a dendritic cell fraction) that have been exposed to a recombinant protein consisting of granulocyte-macrophage colony-stimulating factor (GM-CSF) fused to prostatic-acid phosphatase (PAP), a protein expressed by prostate cancer cells. Upon administration, the vaccine may stimulate an antitumor T-cell response against tumor cells expressing PAP. (NCI05)NCI
code
  • C1985
is someValuesFrom of
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