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AttributesValues
rdf:type
rdfs:label
  • Acetaminophen
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Acetaminophen
NSC_Code
  • 109028
  • 3991
UMLS_CUI
  • C0000970
CAS_Registry
  • 103-90-2
FDA_UNII_Code
  • 362O9ITL9D
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that reduces pain and fever (but not inflammation). It belongs to the family of drugs called analgesics.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39129
PDQ_Closed_Trial_Search_ID
  • 39129
Chemical_Formula
  • C8H9NO2
Legacy_Concept_Name
  • Acetaminophen
CHEBI_ID
  • CHEBI:46195
FULL_SYN
  • ParacetamolSYDTPNSC0003991
  • ParacetamolSYNCI
  • ACETAMINOPHENPTFDA362O9ITL9D
  • AcetaminophenPTNCI
  • AcetaminophenSYDTPNSC0003991
  • APAPABNCI
  • TylenolSYDTPNSC0003991
  • acetaminophenPTNCI-GLOSSCDR0000045165
  • N-(4-Hydroxyphenyl)acetamideSNNCI
  • AcetaminophenPTDCP00589
  • TylenolBRNCI
  • 4-HydroxyacetanilideSNNCI
DEFINITION
  • A p-aminophenol derivative with analgesic and antipyretic activities. Although the exact mechanism through which acetaminophen exert its effects has yet to be fully determined, acetaminophen may inhibit the nitric oxide (NO) pathway mediated by a variety of neurotransmitter receptors including N-methyl-D-aspartate (NMDA) and substance P, resulting in elevation of the pain threshold. The antipyretic activity may result from inhibition of prostaglandin synthesis and release in the central nervous system (CNS) and prostaglandin-mediated effects on the heat-regulating center in the anterior hypothalamus.NCI
code
  • C198
is someValuesFrom of
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