About: G(i) Alpha     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • G(i) Alpha
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • G(i) Alpha
UMLS_CUI
  • C1333649
Legacy_Concept_Name
  • G-i_Alpha
FULL_SYN
  • Adenylate Cyclase-Inhibiting G Alpha ProteinSYNCI
  • G Protein Alpha Inhibiting PolypeptideSYNCI
  • G(i) Alpha ProteinSYNCI
  • G(i) AlphaPTNCI
DEFINITION
  • Human G(i) Alpha Proteins (G-Alpha 1 Family) are 40-kDa guanine nucleotide-binding alpha protein subunits of heterotrimeric G protein transducers (alpha, beta, gamma) in transmembrane signaling systems involved in hormonal regulation of adenylate cyclase. Containing virtually identical/similar beta and gamma chains, G proteins are most distinguished by alpha chains. G(i) proteins (alpha(i) subunit) inhibit cyclase in response to beta-adrenergic stimuli. Specific alpha chain regions appear to interact with guanine nucleotides, receptors, effector enzymes, and G protein beta-gamma complex. G proteins that inhibit adenylate kinase and regulate other plasma membrane enzymes are substrates for pertussis toxin. (NCI)NCI
code
  • C19275
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software