About: Pharmacologic Substance

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Pharmacologic Substance
rdfs:subClassOf	Drug, Food, Chemical or Biomedical Material
Has_NICHD_Parent	Substance
Concept_In_Subset	Clinical Data Interchange Standards Consortium Terminology CDISC SDTM Terminology NICHD Terminology NICHD Pediatric Terminology NICHD Childhood Immunization Terminology CDISC SDTM Intervention Type Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Pharmacologic Substance
UMLS_CUI	C1254351
Contributing_Source	BRIDG CDISC NICHD
ALT_DEFINITION	An active natural, synthetic or semi-synthetic ingredient including endogenous body substance that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the human body, but does not include intermediates used in the synthesis of such ingredient (21 CFR 314.3(b)).CDISC Any substance, other than food, that is used to prevent, diagnose, treat or relieve symptoms of a disease or abnormal condition. Also refers to a substance that alters mood or body function, or that can be habit-forming or addictive, especially a narcotic.NCI-GLOSS An article other than food intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease; or intended to affect the structure or any function of the body. EXAMPLE(S): aspirinBRIDG
Legacy_Concept_Name	Pharmacologic_Substance
CHEBI_ID	CHEBI:52217
FULL_SYN	DrugSYNCI Pharmacologic SubstancePTNCI drugPTNCI-GLOSSCDR0000348921 Drug SubstanceSYNCI Pharmacologic SubstancePTNICHD Pharmacological SubstanceSYNCI PharmaceuticalsSYNCI AgentSYNCI DRUGPTCDISC DrugPTBRIDG Pharmacologic AgentSYNCI Pharmacologic SubstanceSYNCITCGA Pharmaceutical AgentSYNCI
DEFINITION	Any natural, endogenously-derived, synthetic or semi-synthetic compound with pharmacologic activity. A pharmacologic substance has one or more specific mechanism of action(s) through which it exerts one or more effect(s) on the human or animal body. They can be used to potentially prevent, diagnose, treat or relieve symptoms of a disease. Formulation specific agents and some combination agents are also classified as pharmacologic substances.NCI
DesignNote	This category represents ingredients, not drug products.
code	C1909
is rdfs:subClassOf of	Photosensitizing Agent Radiopharmaceutical Compound Nucleic Acid Synthesis Inhibitor Multidrug Resistance Modulator Chemopreventive Agent Drug, Natural Product Bioreductive Agent Adjuvant Anti-infective Agent PROTECTIVE AGENTS ANTINEOPLASTICS Endothelin Receptor Antagonist Combination Medication Biological Products Immunomodulating Agent Enzyme Inhibitor Hormone Antagonist Therapeutic Hormone Agent Affecting Nervous System Agent Affecting Respiratory System CARDIOVASCULAR MEDICATIONS Agent Affecting Blood or Body Fluid Agent Affecting Digestive System or Metabolism Agent Affecting Musculoskeletal System Agent Affecting Organs of Special Senses Agent Affecting Integumentary System Protein Synthesis Inhibitor Prostaglandins, Synthetic Pharmacological Chaperone Cation Channel Blocker
is someValuesFrom of	nodeID://b667750 nodeID://b667751
is Has_NICHD_Parent of	Biological Products

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