About: SRC Family Oncogene     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • SRC Family Oncogene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • SRC Family Oncogene
UMLS_CUI
  • C0919476
Legacy_Concept_Name
  • SRC_Family_Oncogene
FULL_SYN
  • SRC Family OncogenePTNCI
DEFINITION
  • Human SRC Family Oncogenes are mutated variants of Tyrosine Kinase Family Genes, which encode diverse SRC Family Tyrosine Kinases, closely related intracellular non-receptor protein-tyrosine kinases with amino acid sequence similarity to SRC and to Rous sarcoma virus oncogene protein PP60(V-SRC). SRC tyrosine kinases interact with diverse cell-surface receptors and participate in intracellular signal transduction pathways in a variety of hematopoietic cells. Oncogenic SRC kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes. SRC family oncogenes disrupt normal cell function.NCI
code
  • C18540
is rdf:first of
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