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AttributesValues
rdf:type
rdfs:label
  • G Protein-Coupled Receptor
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Receptor
Preferred_Name
  • G Protein-Coupled Receptor
UMLS_CUI
  • C0682972
Legacy_Concept_Name
  • G_Protein-Coupled_Receptor
FULL_SYN
  • G Protein Coupled ReceptorSYNCI
  • G Protein-Coupled ReceptorPTNCI
  • G-Protein Coupled ReceptorSYNCI
  • G Protein-Complex ReceptorSYNCI
  • GPCRSYNCI
  • G Protein-Complex ReceptorsSYNCI
DEFINITION
  • Cell surface receptors that are coupled to G-proteins (GTP-binding protein). G-protein coupled receptors are thought to have seven membrane spanning domains and have been divided into 2 subclasses: those in which the binding site is in the extracellular domain for example receptors for glycoprotein hormones, such as thyroid stimulating hormone (TSH) and follicle-stimulating hormone (FSH) and those in which the ligand binding site is likely to be in the plane of the 7 transmembrane domains for example rhodopsin and receptors for small neurotransmitters and hormones for example muscarinic acetylcholine receptor.NCIOn-line Medical Dictionary
code
  • C18239
is rdf:first of
is rdfs:subClassOf of
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