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AttributesValues
rdf:type
rdfs:label
  • Homologous Recombination
rdfs:subClassOf
Semantic_Type
  • Genetic Function
Preferred_Name
  • Homologous Recombination
UMLS_CUI
  • C0599773
Legacy_Concept_Name
  • Homologous_Recombination
FULL_SYN
  • Homologous RecombinationPTNCI
DEFINITION
  • The process of exchange of genetic material between autonomous replicons, which depends on regions of extensive sequence homology between the participating DNA strands. This process involves double-strand breakage of one participant, resection of the break, and strand invasion, followed by formation, displacement and resolution of the Holliday junction. This process is involved in repairing broken DNA and creating combinations of genes that may be unique from the parent duplexes. Disruptions in this process can result in inviability, premature aging and predisposition to cancers and degenerative diseases.NCI
code
  • C18144
is rdfs:subClassOf of
is someValuesFrom of
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