About: Caspase-3     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Caspase-3
rdfs:subClassOf
equivalentClass
OMIM_Number
  • 600636
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Enzyme
Preferred_Name
  • Caspase-3
UMLS_CUI
  • C0291573
Legacy_Concept_Name
  • Caspase-3
FULL_SYN
  • CASP3SYNCI
  • PARP Cleavage ProteaseSYNCI
  • EC 3.4.22.56SYNCI
  • Cysteine Protease CPP32SYNCI
  • Protein YamaSYNCI
  • SREBP Cleavage Activity 1SYNCI
  • Caspase 3, Apoptosis-Related Cysteine ProteaseSYNCI
  • YamaSYNCI
  • SCA-1SYNCI
  • CPP32SYNCI
  • CPP-32SYNCI
  • CASP-3SYNCI
  • CPP32BSYNCI
  • ApopainSYNCI
  • Caspase-3PTNCI
Swiss_Prot
  • P42574
DEFINITION
  • Caspase-3 (277 aa, ~31 kDa) is encoded by the human CASP3 gene. This protein is involved in the mediation of proteolysis and the activation of apoptosis.NCI
DesignNote
  • Caspase-3 is a central player in mediating apoptosis and is the most widely studied caspase. This protein cleaves and activates caspases 6, 7 and 9, and itself can be processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
code
  • C18031
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 25 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software