About: MLH1 Protein     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:DeprecatedClass, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • MLH1 Protein
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Biologically Active Substance
Preferred_Name
  • MLH1 Protein
OLD_PARENT
  • DNA Repair Protein
OLD_KIND
  • Protein_Kind
OLD_ROLE
  • Protein_Encoded_by_Gene|MLH1 Gene
  • Protein_Plays_Role_In_Biological_Process|Mismatch Repair
  • Protein_Has_Biochemical_Function|DNA Binding Protein
Concept_Status
  • Retired_Concept
FULL_SYN
  • MUTL Protein Homolog 1SYNCI
  • hMLH1 ProteinSYNCI
  • MLH1 Gene ProductSYNCI
  • Mismatch DNA Repair Protein MLH1SYNCI
  • MLH1 ProteinPTNCI
Swiss_Prot
  • P40692
DEFINITION
  • MLH1 protein is a DNA-binding, DNA-mismatch repair protein, of the MutL/HexB family, that dimerizes with PMS2 or MLH3. MLH1 is part of the multi-subunit BASC repair complex containing ATM, BLM, MSH2, MSH6, BRCA1, the RAD50/MRE11/NBS1 complex, and the RFC1/RFC2/RFC4 complex. MLH1 is homologous to MutL, which hydrolyzes ATP. (from OMIM 120436 and NCI)NCI
code
  • C17794
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