About: Reticulon 1     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Reticulon 1
rdfs:subClassOf
OMIM_Number
  • 600865
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Reticulon 1
UMLS_CUI
  • C0217373
Legacy_Concept_Name
  • Reticulon-1
FULL_SYN
  • NSPSYNCI
  • RTN1SYNCI
  • Reticulon 1PTNCI
  • NSP-ASYNCI
  • NSP-BSYNCI
  • NSP-CSYNCI
  • Neuroendocrine-Specific ProteinSYNCI
Swiss_Prot
  • Q16799
DEFINITION
  • Expressed in neural and neuroendocrine tissues by human RTN1 Gene (Reticulon Family), 3 isoforms (A, B, C) of Reticulon 1, with unique N termini, are localized to ER membranes and contain a reticulon domain and 2 large C-terminal hydrophobic domains. RTN1 may be involved in neuroendocrine secretion or membrane trafficking. RTN1-A is a 776-aa 135-kD Ser/Pro-rich protein that contains multiple potential phosphorylation sites; RTN1-B is 356-aa and RTN1-C is 208-aa. RTN1-A and RTN1-B are phosphorylated and expression of RTN1-C is strongly correlated with neuronal differentiation. (NCI)NCI
code
  • C17692
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